Denovo Plus B12 (30 capsules)
DENOVO® PLUS B12 is a dietary supplement used for the metabolic management of low folate & B12 levels associated with symptoms of depression. Patients with symptoms of depression often exhibit low levels of folate & vitamin B12. The human body needs sufficient folate intake to produce the essential neurotransmitters serotonin, dopamine, & norepinephrine. These neurotransmitters alleviate feelings of sadness, anxiety, & gloom. Vitamin B12 helps the body use fats & carbohydrates to create energy, stimulate serotonin production, & reduce stress when taking a minimum of 500 mcg (1/2 mg) daily.
Click here to view full DENOVO® PLUS B12 product brochure.
Age, weight, medications, nutrition, & genetics are among the factors that affect one’s ability to absorb & produce sufficient folate & B vitamins. 16% - 42% of people in the United States lack a necessary enzyme (MTHFR), depending upon ethnicity. The body cannot produce folate & other B vitamins, so when there is a problem with absorption, supplementation is essential.
DENOVO PLUS B12 contains readily absorbable folate (as L-5-methyfolate) & vitamin B12 (as methylcobalamin). This means the body does not require the MTHFR enzyme to absorb the folate in DENOVO PLUS B12. When MTHFR is deficient, the body cannot convert folic acid to usable, active, folate. DENOVO PLUS B12 works to correct the root cause of the problem, not just treat symptoms.the problem, not just treat symptoms.
Each DENOVO PLUS B12 capsule contains 15 mg of (25,000 mcg DFE) folate (as L-5-methyltetrahydrofolate), & 2 mg (2,000 mcg) of vitamin B12 (as methylcobalamin). The recommended daily dosage is one capsule per day, in the morning, which regimen may require up to 14 days for symptom improvement.
Why Denovo Plus B12? Because Denovo Plus B12 contains an active folate that your body can absorb easily and quickly, Denovo Plus B12 is priced significantly lower than similar brands, Denovo Plus B12 does not require a prescription, and Denovo Plus B12 contains adequate amounts of folate & vitamin B 12 for you to feel results.
Denovo Plus B12 can help symptoms of: sadness, anxiety, discouragement, hopelessness, short-temperedness, seasonal "blues", gloominess, despair, irritability, stress, tearfulness, hypersensitivity, fatigue, weakness, low energy, and many more!
Gluten-free, Sugar-free, Dairy-free, Soy-free, & Dye-free
Denovo does NOT contain any undesirable fungal additives.
Click here to read an article from the American Journal of Psychiatry titled 'L-Methylfoate as Adjunctive Therapy for SSRI-Resistant Major Depression: Results of Two Randomized, Double-Blind, Parallel-Sequential Trials'.
Click here to read an article from Healthline titled '9 Benefits of Vitamin B12, Based on Science'
Click here to read an article from Food for the Brain titled 'Methylation and Homocysteine: A Brief Overview'
DRUG FACTS
Active Ingredients: 25,000 mcg DFE of Folate (as 15 mg calcium L-5-methyltetrahydrofolate) & 2,000 mcg vitamin B12 (as 2 mg methylcobalamin)
Inactive Ingredients: microcrystalline cellulose, capsule (gelatin, titanium dioxide), vegetable magnesium stearate, & silica.
Uses: DENOVO® PLUS B12 is a dietary supplement used for the metabolic management of low folate & B12 levels associated with symptoms of depression.
Warnings: Protect from heat, light, & moisture. Keep out of reach of children. Do not purchase if seal is broken.
Folic acid, when administered in daily doses above 0.1 mg, may obscure the detection of B12 deficiency (specifically, the administration of folic acid may reverse the hematological manifestations of B12 deficiency, including pernicious anemia, while not addressing the neurological manifestations). 5-MTHF may be less likely than folic acid to mask vitamin B12 deficiency. Folate therapy alone is inadequate for the treatment of a B12 deficiency. Methylcobalamin is counteracted with the consumption of alcohol. Serum B12 levels may be artificially elevated in patients with alcoholism, liver disease, or cancer. A major depressive episode may be the initial presentation of bipolar disorder. It is generally believed, although not established in controlled trials, that treating such an episode with an antidepressant alone may increase the likelihood of a precipitation of a mixed/manic episode in patients at risk for bipolar disorder. Denovo® plus B12 is not an antidepressant. However, 5-MTHF has been shown to enhance antidepressant effects of known antidepressants. Caution is recommended in patients with a history of bipolar illness. Patients with depressive symptoms should be adequately screened to determine if they are at risk for bipolar disorder since mood elevation in this population is possible. DENOVO® PLUS B12 should always be used under medical supervision.
DIRECTIONS
Take one capsule daily, in the morning, or as recommended by your healthcare professional.
Each bottle contains 30 capsules.
WHAT PEOPLE SAY
"After giving birth, I struggled with post-partum depression. I had been on prescription antidepressants in the past and really did not want to go on one again due to the associated side effects. Denovo was reccomended to me as an alternative. It is truly a fantastic product! It worked just as well, if not better, than the antidepressants I have been on in the past. Denovo helped me feel like myself again! I continue to take it daily because not only does it reduce my irritability and depressed feelings, I feel like it gives me more energy - which I need!"
- Whitney from Louisville, KY
"I have been using Denovo since May of 2019 because I suffer from depression. I was taking four prescriptions to battle my symptoms. Since I began taking Denovo, I have been able to cut down to one prescription. The combination of the prescription antidepressant and Denovo has resulted in my moods leveling off. I do not feel like I am always up or down anymore. I feel amazing! I have not been able to say that in a long time. My husband has also begun taking Denovo and says that he has more energy."
- Lori from Lilburn, GA
Note: The statements in all testimonials are the opinions of the contributor and have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease.
